Appraisal of Clinical Trial Applications in the Cayman Islands

1. Currently, clinical practitioners in the Cayman Islands may undertake research only with the explicit permission of the Health Practice Commission (HPC).

2. The granting of such permission is not trivial given that, by definition, the effectiveness and safety of a medicine or procedure that isthe subject ofsuch a trial does not have wellestablished safety and, or, outcome data (otherwise a trial would be unnecessary).

3. The following advisory note is based around UK clinical trials practice adapted from the resources developed by the National Institute for Health and Care Research at: https://www.ct-toolkit.ac.uk/routemap

Published: 9 January 2026

Publication Type: Guide

Last updated:

Category: 2026, Department of Health Regulatory Services (DHRS), Guide